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Melbourne School of Engineering
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Dr Alexander N. Zelikin

Ph.D., Polymer Chemistry, Moscow State University, Russia, 2003
B.Sc., Polymer Chemistry, Moscow State University, Russia, 2000

Research Fellow

Email:
Telephone: +61 3 8344 9833
Fax: +61 3 8344 4153
Room 1.16, Chemical & Biomolecular Engineering Building 1

Nanostructured Interfaces and Materials (NIMS) Group

Professional Affiliations

  • Member, American Chemical Society

Professional Experience

  • 2007 - 2009: ARC Australian Postdoctoral Fellow, Centre for Nanoscience and Nanotechnology, The University of Melbourne, Australia
  • 2004 - 2006: Research Fellow, Centre for Nanoscience and Nanotechnology, The University of Melbourne, Australia
  • 2003 - 2004: Postdoctoral research associate, Cornell University, Ithaca, USA
  • 2000 - 2001: Visiting scientist, Massachusetts Institute of Technology, Cambridge, USA

Selected Publications

  1. Chong, S.-F.; Chandrawati, R.; Städler, B.; Park, J.; Cho, J.; Wang, Y.; Jia, Z.; Bulmus, V.; Davis, T. P.; Zelikin, A. N.; Caruso. F. "Stabilization of Polymer Hydrogel Capsules via Thiol-Disulfide Exchange." Small 2009, 5, 2601. [link]
  2. Städler, B.; Price, A. D.; Chandrawati, R.; Hosta-Rigau, L.; Zelikin, A. N.; Caruso, F. "Polymer Hydrogel Capsules: En Route Toward Synthetic Cellular Systems." Nanoscale 2009, 1, 68. [link]
  3. Chandrawati, R.; Städler, B.; Postma, A.; Connal, L. A.; Chong, S.-F.; Zelikin, A. N.; Caruso. F. "Engineered Degradable Capsosomes: Cholesterol-Mediated Anchoring of Enzyme-Loaded Liposomes within Disulfide-Stabilized Polymer Carrier Capsules." Biomaterials 2009, 30, 5988. [link]
  4. Chong, S.-F.; Sexton, A.; De Rose, R.; Kent, S. J; Zelikin, A. N.; Caruso, F. "A Paradigm for Peptide Vaccine Delivery Using Viral Epitopes Encapsulated in Degradable Polymer Hydrogel Capsules." Biomaterials 2009, 30, 5178. [link]
  5. Postma, A.; Yan, Y.; Wang, Y.; Zelikin, A. N.; Tjipto, E.; Caruso, F. "Self-Polymerization of Dopamine as a Versatile and Robust Technique to Prepare Polymer Capsules." Chem. Mater. 2009, 21, 3042. [link]
  6. Städler, B.; Chandrawati, R.; Price, A. D.; Chong, S-F.; Breheney, K.; Postma, A.; Connal, L. A.; Zelikin, A. N.; Caruso, F. "A Microreactor with Thousands of Subcompartments: Enzyme-Loaded Liposomes within Polymer Capsules." Angew. Chem. Int. Ed. 2009, 48, 4359. [link]
  7. Sivakumar, S.; Bansal, V.; Cortez, C.; Chong, S-F.; Zelikin, A. N.; Caruso, F. "Degradable, Surfactant-Free, Monodisperse Polymer-Encapsulated Emulsions as Anticancer Drug Carriers." Adv. Mater. 2009, 21, 1820. [link]
  8. Connal, L. A.; Kinnane, C. R.; Zelikin, A. N.; Caruso, F. "Stabilization and Functionalization of Polymer Multilayers and Capsules via Thiol-Ene Click Chemistry." Chem. Mater. 2009, 21, 576. [link]
  9. Price, A. D.; Zelikin, A. N.; Wang, Y.; Caruso, F. "Triggered Enzymatic Degradation of DNA within Selectively Permeable Polymer Capsule Microreactors." Angew. Chem. Int. Ed. 2009, 48, 329. [link]
  10. Priest, C.; Quinn, A.; Postma, A.; Zelikin, A. N.; Ralston, J.; Caruso, F. "Microfluidic Polymer Multilayer Adsorption on Liquid Crystal Droplets for Microcapsule Synthesis." Lab Chip 2008, 8, 2182. [link]
  11. De Rose, R.; Zelikin, A. N.; Johnston, A. P. R.; Sexton, A.; Chong, S-F.; Cortez, C.; Mulholland, W.; Caruso, F.; Kent, S. J. "Binding, Internalization, and Antigen Presentation of Vaccine-Loaded Nanoengineered Capsules in Blood." Adv. Mater. 2008, 20, 4698. [link]
  12. Wang, Y.; Bansal, V.; Zelikin, A. N.; Caruso, F. "Templated Synthesis of Single-Component Polymer Capsules and Their Application in Drug Delivery." Nano Lett. 2008, 8, 1741. [link]
  13. Gupta, J. K.; Tjipto, E.; Zelikin, A. N.; Caruso, F.; Abbott, N. L. "Characterization of the Growth of Polyelectrolyte Multilayers Formed at Interfaces between Aqueous Phases and Thermotropic Liquid Crystals." Langmuir 2008, 24, 5534. [link]
  14. Zelikin, A. N.; Li, Q.; Caruso, F. "Disulfide-Stabilized, Poly(methacrylic acid) Capsules: Formation, Cross-Linking, and Degradation Behavior." Chem. Mater. 2008, 20, 2655. [link]
  15. Zelikin, A. N.; Such, G. K.; Postma, A.; Caruso, F. "Poly(vinylpyrrolidone) for Bioconjugation and Ligand Surface Biofunctionalization." Biomacromolecules 2007, 8, 2950. [link]
  16. Johnston, A. P. R.; Zelikin, A. N.; Caruso, F. "Assembling DNA into Advanced Materials: From Nanostructured Films to Biosensing and Drug Delivery." Adv. Mater. 2007, 19, 3727. [link]
  17. Quinn, J. F.; Johnston, A. P. R.; Such, G. K.; Zelikin, A.; Caruso, F. "Next Generation, Sequentially Assembled Ultrathin Films: Beyond Electrostatics." Chem. Soc. Rev. 2007, 36, 707. [link]
  18. Zelikin, A. N.; Becker, A. L.; Johnston, A. P. R.; Wark, K. L.; Turatti, F.; Caruso, F. "A General Approach for DNA Encapsulation in Degradable Polymer Microcapsules." ACS Nano 2007, 1, 63. [link]
  19. Zawaneh, P. N.; Doody, A. M.; Zelikin, A. N.; Putnam, D. "Diblock Copolymers Based on Dihydroxyacetone and Ethylene Glycol: Synthesis, Characterization and Nanoparticle Formulation." Biomacromolecules 2006, 7, 3245. [link]
  20. Zelikin, A. N.; Zawaneh, P. N.; Putnam, D. "A Functionalizable Biomaterial Based on Dihydroxyacetone, an Intermediate of Glucose Metabolism." Biomacromolecules 2006, 7, 3239. [link]
  21. Zelikin, A. N.; Li, Q.; Caruso, F. "Degradable Polyelectrolyte Capsules Filled with Oligonucleotide Sequences." Angew. Chem. Int. Ed. 2006, 45, 7743. [link]
  22. Zelikin, A. N.; Quinn, J.F.; Caruso, F. "Disulfide Cross-Linked Polymer Capsules: En Route to Biodeconstructible Systems." Biomacromolecules 2006, 7, 27. [link]
  23. Johnston, A. P. R.; Zelikin, A. N.; Lee, L.; Caruso, F. "Approaches to Quantifying and Visualizing Polyelectrolyte Multilayer Film Formation on Particles." Anal. Chem. 2006, 78, 5913. [link]
  24. Zelikin, A. N.; Putnam, D. "Poly(carbonate-acetal)s from the Dimer Form of Dihydroxyacetone." Macromolecules 2005, 38, 5532. [link]
  25. Zelikin, A. N.; Davydova, O. V.; Akritskaya, N. I.; Kargov, S. I.; Izumrudov, V. A. "Conformation of Polyelectrolyte Chains in Dilute Aqueous Solutions Investigated by Conductometry. 4. Influence of Molecular Mass and Charge Density of the Chains on Conformation of Symmetrical Aliphatic Ionene Bromides." J. Phys. Chem. B. 2004, 108, 490. [link]
  26. Zelikin, A. N.; Trukhanova, E. S.; Putnam, D.; Izumrudov, V. A.; Litmanovich, A. A. "Competitive Reactions in Solutions of Poly-L-histidine, Calf Thymus DNA, and Synthetic Polyanions: Determining the Binding Constants of Polyelectrolytes." J. Am. Chem. Soc. 2003, 125, 13693. [link]
  27. Zelikin, A. N.; Litmanovich, A. A.; Paraschuk, V. V.; Sybatchin, A. V.; Izumrudov, V. A. "Conformational Changes of Aliphatic Ionenes in Water-Salt Solutions as a Factor Controlling Stability of Their Complexes with Calf Thymus DNA." Macromolecules 2003, 36, 2066. [link]
  28. Zelikin, A. N.; Putnam, D.; Shastri, P.; Langer, R.; Izumrudov, V. A. "Aliphatic Ionenes as Gene Delivery Agents: Elucidation of Structure-Function Relationship through Modification of Charge Density and Polymer Length." Bioconjugate Chem. 2002, 13, 548. [link]
  29. Zelikin, A. N.; Lynn D. M.; Farhadi, J.; Martin, I.; Shastri, V.; Langer, R. "Erodible Conducting Polymers for Potential Biomedical Applications." Angew. Chem. Int. Ed. 2002, 41, 141-144. [link]
 --- Alex Zelikin

 
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