B.Sc., Applied Science (Medical Biochemistry), Hogeschool Enschede, The Netherlands, 1999

Research Assistant

Email:
Telephone: +61 3 8344 4702
Fax: +61 3 8344 4153

Room 1.06, Chemical & Biomolecular Engineering Building 1

Nanostructured Interfaces and Materials (NIMS) Group

Professional Experience

• 2009 - Present: Research Assistant, Centre for Nanoscience and Nanotechnology, The University of Melbourne, Australia
• 2005 - 2008: Research Assistant, Twente University, The Netherlands
• 2002 - 2005: Research Assistant, Medisch Spectrum Twente, The Netherlands
• 1999 - 2002: Research Assistant, University of Utrecht, The Netherlands

Selected Publications

1. van der Meer, A. D.; Kamphuis, M. M. J.; Poot, A. A.; Feijen, J.; Vermes, I. "Lowering Caveolin-1 Expression in Human Vascular Endothelial Cells Inhibits Signal Transduction in Response to Shear Stress." Int. J. Cell Biology 2009, Art. 532432 [link].
2. Engbers-Buijtenhuis, P.; Kamphuis, M.; van der Sluijs Veer, G.; Haanen, C.; Poot, A. A.; Feijen, J.; Vermes, I. " A Novel Ttime Resolved Fluorometric Assay of Anoikis Using Europium-Labelled Annexin V in Cultured Adherent Cells." Apoptosis 2005, 10, 429. [link]
3. van de Donk, N. W. C. J.; Lokhorst, H. M.; Nijhuis, E. H. J.; Kamphuis, M. M. J.; Bloem, A. C. "Geranylgeranylated Proteins are Involved in the Regulation of Myeloma Growth." Clin. Cancer Res. 2005, 11, 429. [link]
4. van de Donk, N. W. C. J.; Schotte, D.; Kamphuis, M. M. J.; van Marion, A. M. W.; van Kessel, B.; Bloem, A. C.; Lokhorst, H. M. "Protein Geranylgeranylation is Critical for the Regulation of Ssurvival and Proliferation of Lymphoma Tumor Cells." Clin. Cancer Res. 2003, 9, 5735. [link]
5. van de Donk, N. W.; Kamphuis, M. M.; van Kessel, B.; Lokhorst, H. M.; Bloem, A. C. "Inhibition of Protein Geranylgeranylation Iinduces Apoptosis in Myeloma Plasma Cells by Reducing Mcl-1 Protein Levels." Blood 2003, 102, 3354. [link]
6. van de Donk, N. W. C. J.; Kamphuis, M. M. J.; van Dijk, M.; Borst, H. P. E.; Bloem, A. C.; Lokhorst, H. M. " Chemosensitization of Myeloma Plasma Cells by an Antisense-Mediated Downregulation of Bcl-2 Protein." Leukemia 2003, 17, 211. [link]
7. van de Donk, N. W. C. J.; Kamphuis, M. M. J.; Lokhorst, H. M.; Bloem, A. C. "The Cholesterol Lowering Drug Lovastatin Induces Cell Death in Myeloma Plasma Cells." Leukemia 2002, 16, 1362. [link]
8. Popernack, P. M.; Truong, L. T.; Kamphuis, M.; Henderson, A. J. "Ectopic Expression of CCAAT/Enhancer Binding Protein Beta (C/EBPbeta) in Long-Term Bone Marrow Cultures Induces Granulopoiesis and Alters Stromal Cell Function." J. Hematother. Stemcell Res. 2001, 10, 631. [link]